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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK3
All Species:
41.21
Human Site:
S239
Identified Species:
56.67
UniProt:
Q00526
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00526
NP_001249.1
305
35046
S239
Q
L
P
D
Y
K
G
S
F
P
K
W
T
R
K
Chimpanzee
Pan troglodytes
XP_523720
325
36841
S259
Q
L
P
D
Y
K
G
S
F
P
K
W
T
R
K
Rhesus Macaque
Macaca mulatta
XP_001102596
305
34903
N239
Q
L
P
D
Y
K
G
N
F
P
K
W
T
R
K
Dog
Lupus familis
XP_540442
303
34173
S237
Q
L
P
D
Y
K
G
S
F
P
K
W
T
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80YP0
303
33870
S238
Q
M
P
D
Y
Q
S
S
F
P
K
W
S
R
K
Rat
Rattus norvegicus
Q63699
298
33869
S239
S
M
P
D
Y
K
P
S
F
P
K
W
A
R
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
T240
S
L
Q
D
Y
K
N
T
F
P
K
W
K
P
G
Frog
Xenopus laevis
P23437
297
33852
T239
T
M
P
D
Y
K
S
T
F
P
K
W
I
R
Q
Zebra Danio
Brachydanio rerio
NP_998571
298
34001
S239
S
M
P
D
Y
K
P
S
F
P
K
W
A
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
T240
S
L
P
D
Y
K
N
T
F
P
C
W
S
T
N
Honey Bee
Apis mellifera
XP_393450
299
34033
M238
Q
L
R
D
Y
T
S
M
F
P
R
W
E
P
R
Nematode Worm
Caenorhab. elegans
P34556
332
38277
T258
S
L
P
D
Y
K
A
T
F
P
K
W
R
E
N
Sea Urchin
Strong. purpuratus
XP_790847
299
34142
S239
S
L
P
D
Y
K
T
S
F
P
R
W
T
P
Q
Poplar Tree
Populus trichocarpa
XP_002306004
294
33768
T227
L
G
T
P
N
E
D
T
W
P
G
V
T
S
L
Maize
Zea mays
P23111
294
33816
S227
L
G
T
P
N
E
Q
S
W
P
G
V
S
C
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
T227
M
G
T
P
Y
E
D
T
W
R
G
V
T
S
L
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
I235
L
G
T
P
N
E
A
I
W
P
D
I
V
Y
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
96.7
88.5
N.A.
82.6
74.7
N.A.
N.A.
63.6
73.7
73.7
N.A.
62.9
67.2
58.1
69.5
Protein Similarity:
100
93.5
98.3
92.7
N.A.
91.8
84.5
N.A.
N.A.
78
84.5
83.2
N.A.
76.7
80.6
69.5
82.6
P-Site Identity:
100
100
93.3
100
N.A.
73.3
66.6
N.A.
N.A.
53.3
60
66.6
N.A.
53.3
46.6
60
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
80
N.A.
N.A.
60
80
80
N.A.
66.6
60
66.6
80
Percent
Protein Identity:
65.2
64.2
N.A.
65.5
62.3
N.A.
Protein Similarity:
81.6
80.9
N.A.
81.3
77.7
N.A.
P-Site Identity:
13.3
13.3
N.A.
13.3
6.6
N.A.
P-Site Similarity:
33.3
33.3
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
6
0
0
6
0
% C
% Asp:
0
0
0
77
0
0
12
0
0
0
6
0
0
0
0
% D
% Glu:
0
0
0
0
0
24
0
0
0
0
0
0
6
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
77
0
0
0
0
0
0
% F
% Gly:
0
24
0
0
0
0
24
0
0
0
18
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
6
0
0
0
6
6
0
0
% I
% Lys:
0
0
0
0
0
65
0
0
0
0
59
0
6
0
30
% K
% Leu:
18
53
0
0
0
0
0
0
0
0
0
0
0
0
24
% L
% Met:
6
24
0
0
0
0
0
6
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
18
0
12
6
0
0
0
0
0
0
12
% N
% Pro:
0
0
65
24
0
0
12
0
0
95
0
0
0
18
0
% P
% Gln:
36
0
6
0
0
6
6
0
0
0
0
0
0
0
24
% Q
% Arg:
0
0
6
0
0
0
0
0
0
6
12
0
6
48
6
% R
% Ser:
36
0
0
0
0
0
18
48
0
0
0
0
18
12
0
% S
% Thr:
6
0
24
0
0
6
6
36
0
0
0
0
42
6
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
18
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
24
0
0
77
0
0
0
% W
% Tyr:
0
0
0
0
83
0
0
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _